Name: Semaglutid-Seitenkette; Semaglutid-Aktivester-Modifikator; Semaglutid-Seitenkette NHS-Aktivester
Produktabkürzung: tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu
CAS-Nr.: 1118767-15-9
Produktcode: 06040003000
Lagerung: -20±5°C
Die Semaglutid-Seitenkette (tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu) ist eine wichtige Schutzgruppe für Seitenketten bei der Peptidsynthese. Sie weist eine ausgezeichnete Löslichkeit und Stabilität auf und schützt Aminosäureseitenketten wirksam vor unspezifischen Modifikationen oder Abbau während chemischer Reaktionen. Die Semaglutid-Seitenkette wird häufig bei der Festphasenpeptidsynthese und nachfolgenden funktionellen Gruppenmodifikationen verwendet und hilft bei der Kontrolle der Reaktionsbedingungen und Selektivität, minimiert Nebenreaktionen und verbessert so die Produktreinheit und Ausbeute.
I. Bewerbungen
Drug Modification: tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu is utilized in modifying small molecule drugs, proteins, antibodies, and other bioactive molecules. By forming stable amide bonds, it enhances drug solubility, stability, or targeting specificity, thereby improving therapeutic efficacy and safety. Particularly significant in the development of long-acting peptide drugs like Semaglutide, it plays a critical role in optimizing pharmacokinetic properties and therapeutic effects.
Targeted Drug Delivery: Leveraging its high reactivity and biocompatibility, tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu is employed in constructing targeted drug delivery systems. This facilitates precise drug release within specific tissues or cells, enhancing therapeutic efficacy while reducing side effects.
Biological Probes and Diagnostic Reagents: As a component of biological probes or diagnostic reagents, this compound can detect specific molecules or cellular activities within organisms, providing robust support for disease diagnosis and treatment.
II. Production and Storage
Production: The production of tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu is typically carried out by specialized pharmaceutical intermediate manufacturers equipped with advanced synthesis technologies and stringent quality control systems.
Storage: It is recommended to store tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu at -20°C to ensure stability and activity.
III. Supplier Information
Currently, multiple suppliers, including but not limited to Xiamen Sinobestech Biotechnology Co., Ltd., offer tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu. These suppliers possess extensive production experience and rigorous quality control processes, ensuring high-quality products and excellent service for customers.
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| Name | Abbreviation | CAS# |
|---|---|---|
| Somarutopeptide carboxylic acid modifier | tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu | 1118767-16-0 |
| Somarutopeptide active ester modifier | tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu | 1118767-15-9 |
| Somarutopeptide deprotection active ester modifier | HO-Ste-Glu(AEEA-AEEA-OSu)-OH | 1169630-40-3 |
| Somarutopeptide deprotection active ester modifier | HO-Ste-Glu(AEEA-AEEA-OSu)-OH(苄基路线) | 1169630-40-3 |
| Somarutopeptide side chain analogue 2 | tBuO-Ste-Glu(AEEEA-AEEEA-OH)-OtBu | / |
| Somarutopeptide side chain analogue 3 | tBuO-Ste-AEEEA-AEEEEEEA-OH | / |
| Somarutopeptide side chain analogue 4 | tBuO-Bz-Seb-Glu(AEEA-AEEA-OH)-OtBu | / |
| Somarutopeptide sodium salt modifier | tBuO-Ste-Glu(AEEA-AEEA-ONa)-OtBu | / |
| Somarutopeptide side chain analogue 6 | HO-Ste-Glu(AEEA-AEEA-Mal)-OH | / |
| Somarutopeptide side chain analogue 7 | HO-Ara-Glu(AEEA-AEEA-Mal)-OH | / |
| / | HO-Ara-Glu(NH-PEG6-NH-Mal)-OH | / |
| / | HO-Ara-NH-PEG9-NH-Mal | / |
| Somarutopeptide propionaldehyde modified side chain | tBuO-Ste-Glu(AEEA-AEEA-NH-pALD)-OtBu | / |
| Fmoc-Lys Somarutopeptide side chain | Fmoc-Lys(tBuO-Ste-Glu(AEEA-AEEA)-OtBu)-OH | 1662688-20-1 |
| Somarutopeptide side chain analogue 14 | Fmoc-Lys(tBuO-Pal-Glu(AEEA-AEEA)-OtBu)-OH | / |
| Somarutopeptide side chain analogue 15 | Fmoc-Lys(Pal-Glu(AEEA-AEEA)-OtBu)-OH | / |
| / | Fmoc-Lys(tBuO-Ara-Glu(AEEA)-OtBu)-OH | / |
